Renal Stem Cells, Tissue Regeneration, and Stem Cell Therapies for Renal Diseases

Renal Stem Cells, Tissue Regeneration, and Stem Cell Therapies for Renal Diseases

1Center for Molecular Biotechnology, Department of Molecular Biotechnology and Health Sciences, 10126 Torino, Italy 2Department of Medicine and Clinical Science, Gunma University Graduate School of Medicine, Maebashi, Gunma 371-8511, Japan 3Departments of Physiology and Biophysics and Medicine, University of Southern California, Los Angeles, CA 90033, USA 4Department of Internal Medicine, Jikei...

Stem cells and renal regeneration.

The role of embryonal or adult stem cells, in particular bone marrow (BM)-derived stem cells, in regenerating the kidney after injury has been the subject of intensive investigation. BM-derived stem cells have been shown to give rise to small numbers of most renal cell types, including tubular cells, mesangial cells, podocytes, vascular cells and interstitial cells. However, the role this infre...

Trophic Factors from Tissue Stem Cells for Renal Regeneration

Stem cell therapies against renal injury have been advancing. The many trials for renal regeneration are reported to be effective in many kinds of renal injury models. Regarding the therapeutic mechanism, it is believed that stem cells contribute to make regeneration via not only direct stem cell differentiation in the injured space but also indirect effect via secreted factors from stem cells....

Amniotic Fluid Stem Cells and Their Application in Cell-Based Tissue Regeneration

Thermogelling 3D Systems towards Stem Cell-Based Tissue Regeneration Therapies.

Stem cell culturing and differentiation is a very important research direction for tissue engineering. Thermogels are well suited for encapsulating cells because of their non-biotoxic nature and mild sol-gel transition as temperature increases. In particular, thermogels provide a 3D growth environment for stem cell growth, which is more similar to the extracellular matrix than flat substrates, ...